Kinase Browser

Detailed locus information, expression profile, gene disruption strategy, and phenotype assay data.

Detailed Locus Information for CNAG_04118T0
SpeciesCryptococcus neoformans var. grubii H99
Gene AnnotationCMGC/CDK/CRK7 protein kinase
Gene SymbolUnknown
Kinase SuperfamilyProtein kinase-like (PK-like)
Kinase FamilyProtein kinases, catalytic subunit
KEGG Linkout KEGG::CNI04290 
Genome Browser JBrowse link goes here. Sequence information also available from JBrowse.
Kinase Prediction
Kinomer Result
PredictionScoreE-value
CMGC294.11.1e-87
Microbial Kinome Result
PredictionScoreE-value
ePK227.38e-68
Functional Annotation
KEGG Annotation
KO AccessionE-valueScore
K00916 KEGG 1.1e-203 677.9
Amino Acid SequenceMSGRPFKRESWRPTKRPPTFPAAIQQPPVSSANALPARTWGGAPVPTAPKRFERDPSLNVKEEGHSSRWDDRGSNSGKWDQRDDRSRYGNSGNGKRRHSPSRQLDSTRDERFSSARRSYSPSAPDPSPADSSNYPATRRPLPPAQPPASHHRTPARTRRPSPDYGTSGPAAKKRKGGARGRESPDYGVGSKEDAASSYRRSPSPLSSRSRSRTRSRSLSPAPSHHSQSHSYSHSQTPTHTYTPSQSYRKRSPSPATNDRRLSSGRWGKRDRYNNHKYGKYDKDDRNGKSDSRDNGWEKESNRNWRDRDTHRDGHRRDRRAGDRGGRQDKDWRQDKEYEYDRRDRERDRDRERDRDRDSGWEASRRERDYPPTGPRGYTSSASQLRQDYGTAPSPQRLVHPQAPPSPGNFYDRRRDSSDSYGHQNHSYGQRQGRSPMQDREYPSRSNFVTNANANTIVGTFTPRKWGESGRYPYEQSYQPPSTVSRATSVSREYLPSPQHSNAPPAATSDTVPFPVNPPAPVYPSQSMSFAEYIPKAEEPNSVPPPQLESSVQPLPDTAGPTAELQTRTSPVKISFGQPSGGAVKKGWKSISPKKKARVNLFDEDEEEVQGAKGEKGDRKEMAPEGEQATIGEALPHPDTLIHRLTLASTRYTTLLTSLPAPLRAAFDSFSTLPSSPPPPPFDLFLDEYLGKKARDDEVKRVEEVWHAKEEWEREEEMGRRYLEEVGKGGRVEGVNVAPVERGAARVSPAAVVVAPKPEPELAPMPALGPELQAPAPRAEPQPQTQVPIPLPAVPTVYQKLAAVGEGTYGKVYKAISLITHQPVALKRIRMENEKDGFPVTAMREIKLLQMLQHENVLRLVEMVVERGGVYMVLEYMEFDLTGLLAHPEIKFSPANIKSLSHQMLSGLSYLHHQSILHRDMKGSNILVNSRGELKLADFGLARVYAKKRREDYTNRVITLWYRSPELLMGETIYGPEVDMWSAGCIILELYTTKPIFQGSDELNQLEIIYGLLGTPTEAEWPSVKELPWYELVKPKEEIGSRFRTSFAKWLSPAALDLVEGLLFYDPSQRLLADSALQTDYFLMEEPAMEKPTQLEGMGEHHEMSAKAERRRRKIEGGE
Expression Data
Notation Condition Normalized Raw Expression
A YPD 30°C, concentration: 2x 10^8 cells/ml 3451
B YPD 30°C, concentration: 5x10^7 cells/ml 3567
C YPD 30°C, fluconazole treatment, concentration: 5x10^7 cells/ml 3639
D YPD 30°C, SDS 0.01% treatment, concentration: 5x10^7 cells/ml 3634
E YPD 37°C, concentration: 5x10^7 cells/ml 4022
F YP+galactose 30°C, concentration: 2x10^8 cells/ml 3761
Gene Disruption Strategy
Primer NameDescriptionPrimer Sequence
L1CNAG_04118 5' flanking region primer 1TCAGCGAGATGATAGGTCG
L2CNAG_04118 5' flanking region primer 2TCACTGGCCGTCGTTTTAC CCGCTATCTCTATCTCTGTCC
R1CNAG_04118 3' flanking region primer 1CATGGTCATAGCTGTTTCCTGGACAAGATAAAGATTGGCGG
R2CNAG_04118 3' flanking region primer 2CGCCATCTCCTTTCTATCG
SOCNAG_04118 diagnostic screening primer, pairing with B79CAAAAGAGAATCCTGGAGACC
POCNAG_04118 Southern blot probe primerGGAGAATGAGTCAAATGCTG
STMNAT#212 STM primerAGAGCGATCGCGTTATAGAT
STM commonSTM common primerGCATGCCCTGCCCCTAAGAATTCG